Cyclopia

Case contributed by Dr Manisha Langar

Presentation

A Gujjar patient presented for routine antenatal ultrasound in third trimester for the first time.

Patient Data

Age: 29 years
Gender: Female
Ultrasound

Single intrauterine fetus was seen.

Polyhydramnios

A single midline orbit and an overlying process was seen (proboscis).

Fetal head size was small for gestation age & holoprosencephaly was seen. 

Nasal bones were absent. Fetal lips were normal.

Case Discussion

Cyclopia is an extremely rare type of congenital malformation & is part of a spectrum of anomalies occurring in holoprosencephaly.

This group of congenital anomalies occurs due to to abnormal differentiation & cleavage of the prosencephalon. There is anomalous formation of the central cavity of the orbit, with absence of the nasal cavity. A rudimentary bony process is formed over the orbital cavity called proboscis.

True cyclopia is an extreme form, where  only a single orbit is present. But two globes may be found in different degrees of fusion, called synopthalmos.

Associated mid line facial deformities like midfacial clefts, primitive nasal structures & hypotelorism, may be there.

PlayAdd to Share

Case information

rID: 34442
Case created: 20th Feb 2015
Last edited: 28th Sep 2015
System: Obstetrics
Inclusion in quiz mode: Excluded

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.