Cystic partially differentiated nephroblastoma

Case contributed by Tanzilur Rahman , 25 Sep 2024
Diagnosis certain
Changed by Joachim Feger , 9 Oct 2024
Disclosures - updated 27 Nov 2023: Nothing to disclose

Updates to Freetext Attributes

Description was changed:

Histopathology report-

Microscopic description:

sections from the cauliflower-like growth reveal the features of a malignant tumortumour with the following features:

  • cysts lined with flat/cuboidal/hobnail cells (or are denuded)

  • epithelial elements consist mainly of mature and immature/abortive tubules and small papillae resembling immature glomeruli

  • nephroblastomatous epithelial elements

  • islands of undifferentiated blastema and differentiated mesenchymal elements

  • focally, the septal elements protrude into the cystic spaces in microscopic papillary folds

  • the growth has extended up to distal margin of ureter

  • lymphovascular invasion: seen

Histopathological diagnosis - nephroureterectomyDiagnosis

Nephroureterectomy with bladder cuff: favors, cystic partially differentiated nephroblastoma.

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