Cytotoxic lesion of the corpus callosum
Citation, DOI & case data
Seizures, fever and mental confusion.
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There is a focal lesion of the splenium of the corpus callosum with T1 iso-intense signal, high signal on T2, and FLAIR and restriction of diffusion with no enhancement.
Cytotoxic lesions of the corpus callosum (CLOCC) are acquired lesions. CLOCC are secondary lesions associated with various entities including seizure(with or without antiepileptic medication), metabolic disorders, (such as hypoglycemia, hypernatremia, acute alcohol poisoning, malnutrition, and Vit B12 deficiency ), malignancy, lupus erythematosus, eclampsia and status migrainosus.
Follow-up is recommended.
Additional Contributor: DR BOUKHAMLA MOHAMED CHERIF, radiologist.
- 1. Cytotoxic Lesions of the Corpus Callosum That Show Restricted Diffusion: Mechanisms, Causes, and Manifestations Jay Starkey 1, Nobuo Kobayashi 1, Yuji Numaguchi 1, Toshio Moritani 1,RadioGraphics 2017
- 2. Cytotoxic lesion of corpus callosum in cerebral venous thrombosis—a case report Tamaghna Ghosh, Simran Tanwar, Shishir Chumber & Kavita Vani, Egyptian Journal of Radiology and Nuclear Medicine 2021