Demyelination

Case contributed by Austin Neuropathology

Presentation

30 year old male presenting with right sided symptoms

Patient Data

Age: 30
Gender: Male
MRI

MRI demonstrates a focal periventricular lesion with high T2, low T1 and no significant enhancement.  

Pathology

Neurofilament antibody demonstrating axonal sparing and Luxol Fast Blue showing almost complete demyelination, with myelin debris in macrophages.

Case Discussion

Although not as prominent as in some cases, there is the appearance of a number of concentric alternating high and low bands on T2 wighted imaging, which raises the possibility of Balo concentric sclerosis, a variant of MS

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Case information

rID: 10691
Case created: 6th Sep 2010
Last edited: 15th Oct 2015
Inclusion in quiz mode: Included

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