Diffuse astrocytoma NOS

Case contributed by Ahmed Abdrabou


Behavioral changes, drowsiness, and attacks of convulsion.

Patient Data

Age: 20 years
Gender: Female

Diffuse enlargement and abnormal signal alteration of both thalami, caudate nuclei, insular regions and medial temporal cortices bilaterally. They display iso intense signal in T1 and bright signal in T2/FLAIR without diffusion restriction or post contrast enhancement.

Diagnosis: Grade II astrocytoma (pathologically proven)

Case Discussion

 Grade II astrocytoma (pathologically proven).

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a diffuse astrocytoma NOS.

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