Diffuse astrocytoma NOS
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At the time the case was submitted for publication Ahmed Abdrabou had no recorded disclosures.View Ahmed Abdrabou's current disclosures
Behavioral changes, drowsiness, and attacks of convulsion.
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Diffuse enlargement and abnormal signal alteration of both thalami, caudate nuclei, insular regions and medial temporal cortices bilaterally. They display iso intense signal in T1 and bright signal in T2/FLAIR without diffusion restriction or post contrast enhancement.
Diagnosis: Grade II astrocytoma (pathologically proven)
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Grade II astrocytoma (pathologically proven).
Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a diffuse astrocytoma NOS.
- Osborn A, Blaser S, Salzman K. Encyclopedia of Diagnostic Imaging. AMIRSYS. (2008) ISBN:0721629059. Read it at Google Books - Find it at Amazon
- Hegde AN, Mohan S, Lath N et-al. Differential diagnosis for bilateral abnormalities of the basal ganglia and thalamus. Radiographics. 2011;31 (1): 5-30. Radiographics (full text) - doi:10.1148/rg.311105041 - Pubmed citation
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