Diffuse astrocytoma NOS (gemistocytic)

Case contributed by Dr Hani Salam

Presentation

Headaches.

Patient Data

Age: Young adult
MRI

MRI brain

A very large heterogenous mass occupies much of the frontal lobe on the left. It has areas of cyst formation with thin peripheral enhancement. On FLAIR the cystic areas demonstrate variable signal. 

Case Discussion

This case demonstrates fairly typical (pathologically proven) features of a gemistocytic astrocytoma. Although they are considered WHO grade II tumours, they have a poorer prognosis than other grade II astrocytomas. 

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumours, this tumour would, therefore, be designated as a gemistocytic astrocytoma NOS.

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Case information

rID: 9592
Case created: 2nd May 2010
Last edited: 15th Jun 2017
Inclusion in quiz mode: Included

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