Diffuse astrocytoma NOS (gemistocytic)

Case contributed by Dr Hani Salam



Patient Data

Age: Young adult

MRI brain

A very large heterogenous mass occupies much of the frontal lobe on the left. It has areas of cyst formation with thin peripheral enhancement. On FLAIR the cystic areas demonstrate variable signal. 

Case Discussion

This case demonstrates fairly typical (pathologically proven) features of a gemistocytic astrocytoma. Although they are considered WHO grade II tumors, they have a poorer prognosis than other grade II astrocytomas. 

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a gemistocytic astrocytoma NOS.

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Case information

rID: 9592
Published: 2nd May 2010
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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