Presentation
Headache, seizure, left side body weakness and sometimes nausea/vomiting.
Patient Data
Cortico-subcortical abnormal signal intensity involving the right fronto-temporo-parietal lobes causing effacement of the right lateral ventricle. It is returning low to iso-signal in T1 WI, high signal in T2/FLAIR images without diffusion restriction in DWI and corresponding ADC map. No contrast enhancement is noted in the lesion in post contrast sequences.
Case Discussion
The imaging features are in favor of a diffuse astrocytoma (probably IDH-wt given age) with gliomatosis cerebri growth pattern.
Note: In the 2016 update of WHO classification of CNS tumors, gliomatosis cerebri was removed as a stand-alone diagnosis.
Unfortunately histology is unavailable for confirmation.
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