Diffuse large B cell lymphoma

Case contributed by Ammar Haouimi
Diagnosis almost certain

Presentation

Severe back pain at the lower dorsal region.

Patient Data

Age: 75 years
Gender: Female
mri

The MRI sequences demonstrate a lobulated left paraspinal mass at T9-T11 level, measuring 63 x 48 x 35 mm extending into the spinal canal through the T9-T10 and T10-T11 foramina, compressing the adjacent segment of the spinal cord which is displaced to the right. It displays a low signal on T1, high signal on T2 and STIR with a heterogeneous enhancement on postcontrast sequences.

Another paravertebral soft tissue mass of retroperitoneal location is seen at T12 level of similar signal and enhancement measuring 38 x 30 x 13 mm, invading the diaphragm and most likely the upper pole of the left kidney.

Moderate splenomegaly (15 cm).

Case Discussion

MRI features of left paraspinal masses with two components: the upper component is located at T9-T11 level and shows an intraspinal extension through the adjacent T9-T10 and T10-T11 foramina, and that located at T12 level shows invasion of the left hemidiaphragm and most likely the upper pole of the left kidney. 

A CT-guided paraspinal biopsy was performed with histopathological exam and immunohistochemistry study which confirm the diagnosis of a diffuse large B cell lymphoma.

The main differential diagnoses in such location with intraspinal extension are neurogenic tumors.

 

Additional contributor: ZE. Boudiaf MD CHU, Constantine Algeria

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