Diffuse spinal metastatic deposits
Presents with acute flaccid paralysis.
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There is diffuse loss of marrow signal in the whole spine, with collapse of T4 (pathological fracture) vertebral body. This is well demonstrated on the T1W images.
At this level, there is a soft tissue mass encroaching on the thecal sac compressing the cord and extending into the left pedicle/lamina.
A segment 6 liver lesion which is hyperintense on T2 imaging is also evident
Patient with known prostate cancer. This case demonstrates the loss of marrow signal (especially on the T1W images) due to diffuse metastatic disease, in this case prostate cancer.
- Messiou C, Cook G, deSouza NM. Imaging metastatic bone disease from carcinoma of the prostate. Br. J. Cancer. 2009;101 (8): 1225-32. doi:10.1038/sj.bjc.6605334 - Free text at pubmed - Pubmed citation
- Robert Dreicer, MD, MS, FACP. Using MRI to Detect Bone Metastases in High-Risk Prostate Cancer Patients. 2007;2007: .
- Lecouvet FE, Geukens D, Stainier A et-al. Magnetic resonance imaging of the axial skeleton for detecting bone metastases in patients with high-risk prostate cancer: diagnostic and cost-effectiveness and comparison with current detection strategies. J. Clin. Oncol. 2007;25 (22): 3281-7. doi:10.1200/JCO.2006.09.2940 - Pubmed citation