Diffuse splenic calcification - systemic lupus erythematosus
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At the time the case was submitted for publication Stefan Bernard van der Westhuizen had no recorded disclosures.View Stefan Bernard van der Westhuizen's current disclosures
Female patient known with systemic lupus erythematosus on treatment. Now presented with deteriorating respiratory function. An HRCT chest was requested.
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An incidental finding of numerous calcifications in a tightly grouped distribution are demonstrated throughout the spleen. Note the spared peripheral rim of splenic parenchyma and capsule.
The patient did have features of collagen vascular disease associated ILD on chest imaging (not shown).
Diffuse splenic calcification is a rare manifestation of systemic lupus erythematosus (SLE) and the distinctive calcification pattern can hint at the diagnosis. Splenic calcification secondary to granulomatous disease should be excluded in endemic areas.
- Elzein F, Elzein S, Albalawi R. Splenic Calcification in Systemic Lupus Erythematosus. BMJ Case Rep. 2017;2017:bcr-2017-222206. doi:10.1136/bcr-2017-222206 - Pubmed
- Winter T & Shaaban A. The Characteristic Splenic Calcifications of Systemic Lupus Erythematosus. Abdom Radiol. 2020;46(2):607-8. doi:10.1007/s00261-020-02659-4 - Pubmed