Discitis osteomyelitis L2/3 - Candida
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Patient with chronic discitis osteomyelitis due to chronic infection with Candida albicans.
Spinal column, L2-3: Fungal microorganisms identified, consistent with Candida.
Sections show the specimen to consist of pieces of cartilage, including cartilage end-plate, lamellar bone, paravertebral soft tissue including skeletal muscle, adipose tissue, and a portion of peripheral nerve. Acute, subacute and chronic inflammation is observed. Granulation tissue is evident. Degenerative and reactive changes are also seen. The methenamine silver stained sections confirm the presence of fungal microorganisms that display yeast-like forms with focal budding. Hyphae are also seen. The appearance is consistent with Candida. Some cystic structures contain small Gram-negative structures that could represent degenerative bacteria, or degenerate material showing calcification. Microorganisms are not identified in the ZN-stained sections. There is no evidence of metastatic carcinoma in this material.