Double cortex syndrome
Intractable seizure and developmental delay.
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MRI of an 8 year old demonstrates a continuous ribbon of grey matter seen just deep to the cortex, separated from it with a thin layer of white matter. The overlying brain demonstrates some shallowness of sulci. Incidental cavum septum pellucidum et vergae is noted.
4 case question available
This case illustrates typical and obvious features of double cortex (aka band heterotopia) without obvious lissencephaly. This is likely to be x-linked (female patient) due to mutations of the DXC gene located on the long arm of chromosome X.