Down syndrome subpleural cysts

Case contributed by Dr Jeremy Jones


Down syndrome. Poor exercise tolerance. Previously fixed ASD.

Patient Data

Age: 13 years
Gender: Male

Extensive interstitial opacities bilaterally with cystic ring shadows. Superimposed right perihilar airspace opacification.  Possible small effusions.


Extensive cystic changes throughout both lungs. The cysts are predominantly in a subpleural distribution. Background ground glass change.

Case Discussion

As demonstrated on the plain radiograph, this child has extensive lung disease. There are multiple cysts which are predominantly subpleural (peripherally and along the fissures).

Subpleural cysts have been described in the literature in patients with Down syndrome.

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Case information

rID: 24179
Published: 30th Jul 2013
Last edited: 27th Feb 2016
System: Chest
Inclusion in quiz mode: Included

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