Ductal carcinoma in situ

Case contributed by Dr Garth Kruger

Presentation

Routine mammogram study.

Patient Data

Age: Adult
Gender: Female
Mammography

Single benign lobular calcifications and not anything else of note.

Mammography

One year later

Developing heterogeneous microcalcifications deep and lateral to the areola and in the deep central parenchyma.

Mammography

Mag view shows the heterogeneous nature of the calcifications.

X-ray

Specimen radiograph showing the mammotome clip and localization wires of the sample.

Annotated image

Six months later

Follow up 6 months later. Note the surgical clip and the small area of fat necrosis adjacent to the clip. There is now a developing group of heterogeneous calcifications laterally in the right breast (arrowed) highly suggestive of a developing DCIS focus. If you refer back to the initial image this area was clear of microcalcifications.

Case Discussion

The calcifications of DCIS underestimate the extent of disease. The importance of clear surgical margins is illustrated in this case. Note how the calcifications run almost to the margin of the specimen radiograph at the 2 o'clock radian.

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Case information

rID: 21320
Published: 16th Jan 2013
Last edited: 20th Oct 2019
System: Breast
Inclusion in quiz mode: Excluded

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