Dysembryoplastic neuroepithelial tumor (DNET)

Case contributed by Frank Gaillard



Patient Data

Age: Adult

Selected images from an MRI through the temporal lobes of a patient with seizures demonstrates a high T2, low T1 region within the mesial temporal lobe on the right. The central high T2 region does not attenuate on FLAIR. No contrast enhancement. 

Case Discussion

The patient went on to have a resection. 


 A low-grade glioneuronal tumor is located in the cortex and white matter and contains cystic elements. Floating neurons are observed. Neurocytic-type cells are also noted. In addition to the dysembryoplastic neuroepithelial tumor, varying degrees of cerebral microdysgenesis are also observed, represented by small aggregates of neurons and neurocytic type cells, and increased numbers of ganglion type cells within white matter. Mesial temporal sclerosis is not defined.

Final Diagnosis: dysembryoplastic neuroepithelial tumor (DNET)

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