Dysembryoplastic neuroepithelial tumour (DNET)

Case contributed by A.Prof Frank Gaillard

MRI through the temporal lobes of a patient with seizures demonstrates a high T2, low T1 region within the mesial temporal lobe on the right. The central high T2 region does not attenuate on FLAIR.

Case Discussion

Final Diagnosis:

Brain, right temporal: Dysembryoplastic neuroepithelial tumour (DNET).

Microscopic Description:

Sections confirm a dysembryoplastic neuroepithelial tumor within the mesial block. A low grade glial neuronal tumor is located within cortex and white matter, and contains cystic elements. Floating neurons are observed. Neurocytic-type cells are also noted. In addition to the dysembryoplastic neuroepithelial tumor, varying degrees of cerebral microdysgenesis are also observed. This is represented by small aggregates of neurons and neurocytic type cells, and increased numbers of ganglion type cells within white matter. Mesial temporal sclerosis is not defined.

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Case information

rID: 4088
Case created: 18th Jul 2008
Last edited: 12th Jun 2016
Inclusion in quiz mode: Included

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