Enostosis versus sclerotic bone metastasis

Case contributed by Mohamed Saber
Diagnosis almost certain

Presentation

Abdominal pain. A known case of breast cancer was operated on five years ago.

Patient Data

Age: 30 years
Gender: Female

A right iliac bone well-defined sclerotic bony lesion with finely irregular outline.

Midline pelvic cystic lesion measures 7x8x8 cm. Right iliac bone well-defined ovoid densely sclerotic bony lesion measures 15mm with no associated aggressive features or para-osseous soft tissue masses.

Annotated image

The annotated image shows the attenuation measurements of this lesion, with a mean density (AV) of 1273 HU, and a maximum density of 1379 HU.

Case Discussion

Enostosis versus sclerotic bone metastases is a common diagnostic dilemma in patients with known primary cancer.  One study 1 has suggested that a sclerotic bone lesion can be diagnosed as a bone metastasis versus bone island if its mean attenuation is <885 HU and maximum attenuation is <1060 HU with a 95% sensitivity and a 96% specificity for both values.

Following this study, the attenuation measurements of this case lesion are highly suggestive of enostosis.

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