Ependymoma

Case contributed by Ryan Thibodeau
Diagnosis certain

Presentation

Persistent upper back pain following a fall. Reports upper extremity paresthesias.

Patient Data

Age: 65 years
Gender: Male
mri

There is an enhancing, well-circumscribed, expansile mass with mixed solid and fluid components within the central portion of the spinal cord from the inferior endplate of C6 to T1. On T2-weighted images, there is a hypointense rim seen at the periphery of the lesion. There is T2/STIR hyperintensity at the cranial aspect of the lesion which extends to C5.

Case Discussion

This is a spinal ependymoma. The patient underwent C6-T2 laminectomy and resection of the lesion. Histopathologic examination showed evidence of a WHO grade 2 ependymoma without evidence of anaplasia. On immunohistochemistry stains for Ki-67 and PHH3 (B1), there was no significant proliferative activity (Ki-67: <2% and no appreciable mitosis on PHH3).

Co-author:
Rushali Kothari

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