Expansile and lytic skeletal metastases from renal cell caricnoma
Diagnosis almost certain
Presentation
Pain in the left humerus even at rest with raised serum calcium level.
Patient Data
Age: 75 years
Gender: Male
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Central, diaphyseal, bubbly, expansile, lytic lesion involving the mid-shaft of the left humerus with no evidence of periosteal reaction or calcifications.
Case Discussion
Patient also had multiple liver metastases; USG-guided FNAC analysis of liver secondaries reveal metastatic renal cell carcinoma.
Renal metastases in the bone are generally solitary, and are invariably lytic, expansile lesion. This lesion is hypervascular with no periosteal reactions.
Expansile lytic bone lesion could also be due to thyroid metastases.