Expansile and lytic skeletal metastases from renal cell caricnoma

Case contributed by Subash Thapa
Diagnosis almost certain

Presentation

Pain in the left humerus even at rest with raised serum calcium level.

Patient Data

Age: 75 years
Gender: Male

Central, diaphyseal, bubbly, expansile, lytic lesion involving the mid-shaft of the left humerus with no evidence of periosteal reaction or calcifications.

Case Discussion

Patient also had multiple liver metastases; USG-guided FNAC analysis of liver secondaries reveal metastatic renal cell carcinoma.

Renal metastases in the bone are generally solitary, and are invariably lytic, expansile lesion. This lesion is hypervascular with no periosteal reactions.

Expansile lytic bone lesion could also be due to thyroid metastases.

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