Extramedullary hematopoiesis - beta-thalassemia major

Case contributed by Bahman Rasuli
Diagnosis certain


Clinical concerns of lung mass

Patient Data

Age: 40 years
Gender: Female

Diffuse expansion of osseous medullary spaces, coarsened trabeculations of the ribs and vertebrae, and paravertebral extramedullary hematopoiesis.

Cardiomegaly, prominent main pulmonary artery (44 mm), splenectomy and high attenuation liver (iron overload) - all part of the underlying beta-thalassemia major.

Case Discussion

This case demonstrates an array of findings of beta-thalassemia major.

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