Fibrolamellar hepatocellular carcinoma

Case contributed by Dr Ian Bickle

Presentation

A teenager presents with a palpable right upper quadrant mass. No past medical history.

Patient Data

Age: 15-year-old
Gender: Male
Modality: CT

Huge heterogeneous enhancing mass involving segments 4 and 5 of the liver.

No capsule extension. 

Case Discussion

Fibrolamellar hepatocellular carcinoma is a distinct variant of generic hepatocellular carcinoma.

The 5 distinct aspects compared to generic HCC are:

  • young age at presentation -  young adults (15 to 40 years of age)
  • no association with cirrhosis
  • usually large at presentation
  • not associated with raises serum alpha feto protein
  • less aggressive with a better 5-year survival

On cross sectional imaging the tumour is usually large, heterogeneous, enhances most in the arterial phase and may have a central 'scar' like component.

PlayAdd to Share

Case Information

rID: 32543
Case created: 1st Dec 2014
Last edited: 22nd Dec 2016
Inclusion in quiz mode: Included

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.