Fibrous dysplasia - base of skull

Case contributed by Frank Gaillard
Diagnosis almost certain


Long standing deformity. Now endocrine disturbance.

Patient Data

Age: 45 years
Gender: Male

Facial bones


The bone of the left side of the skull and face, also involving crista galli and the mandible, is expanded with a characteristic ground-glass sclerotic appearance, typical of fibrous dysplasia. Vaguely seen is an expansion of the pituitary region and a pituitary mass, most likely a macroadenoma. 

Typical MRI features of fibrous dysplasia with heterogeneous but predominantly low signal change within the affected bones (skull, face and mandible on the left). Pituitary mass also noted on axial images. 

Case Discussion

Very typical appearances of fibrous dysplasia. 

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