Focal cortical dysplasia - Taylor type IIb

Case contributed by Dr Andrew Lawson

Presentation

Seizures.

Patient Data

Age: 46
Gender: Female

At the posterior aspect of the right superior frontal sulcus, is a moderate sized area of poor grey-white matter differentiation with cortical thickening and FLAIR hyperintensity that tapers toward the ventricle.

Conclusion: Focal cortical dysplasia.

Complete resection.

Case Discussion

Pathology report:

The sections show cerebral cortex and white matter. Mild gliosis of the sub-pial molecular layer is noted as well as accumulation of corpora amylacea. There is disturbance of laminar architecture in both specimens which is more extensive in specimen 1. Marked neuronal dystrophy and neuronomegaly is also seen in specimen 1 and there are numerous balloon cells some of which are bi-nucleate. These changes are not seen in specimen 2. Moderate numbers of neurones are noted in white matter in both specimens. Myelination is normal and there is no evidence of tumour. The features are of focal cortical dysplasia - Taylor Type IIB. The surgical margins are clear of dysplastic cortex.

DIAGNOSIS: 1&2: Frontal cortex: Focal cortical dysplasia - Taylor Type IIB.

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Case information

rID: 26376
Case created: 18th Dec 2013
Last edited: 2nd Oct 2015
Inclusion in quiz mode: Included

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