Forehead squamous cell carcinoma and parotid Warthin tumour

Case contributed by Dr Bruno Di Muzio


Lesion in salivary gland on ultrasound.

Patient Data

Age: 81-year-old
Gender: Male
Exophytic left frontal skin lesion, with deep invasion into the subgaleal fat to the margin of the bone. No convincing evidence of cortical erosion or secondary bone changes. If there is clinical concern, MRI could better evaluate this. Small intraparotid node on the left within the superficial lobe. No cervical lymphadenopathy detected. Marked calcification demonstrated within the internal carotid arteries bilaterally. This could be further assessed with a community ultrasound if clinically indicated.

Case Discussion

MICROSCOPIC DESCRIPTION: 1. Sections show a well-demarcated, thinly encapsulated proliferation of oncocytic cells forming cysts and papillae within a stroma heavily infiltrated by a polymorphous population of bland lymphocytes. The lesion is fully excised. There is no evidence of malignancy. Adjacent salivary gland is unremarkable. 2. Sections show ulcerated sun damaged skin with attached subcutis and deep fascia. There is a poorly differentiated carcinoma extending from the ulcer base as solid sheets that invade subcuticular fat and skeletal muscle. The tumour does not invade through the deep fibrous fascia. Tumour cells are pleomorphic with large nucleoli containing prominent nucleoli and frequent mitotic figures. There is focal keratinisation and occasional intercellular bridges. Tumour invades nerves but lymphovascular invasion is not seen. The tumour is well clear of the skin margins. Sections of bone show no evidence of tumour.


1. Left parotidectomy: Warthin's tumour, completely excised.

2. Scalp lesion: Poorly differentiated squamous cell carcinoma invading the aponeurotic layer, not involving bone, well clear of skin and soft tissue margins.

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Case information

rID: 50083
Published: 22nd Dec 2016
Last edited: 10th Feb 2017
System: Head & Neck
Tag: rmh
Inclusion in quiz mode: Excluded

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