Functional MRI - language task

Case contributed by Dr Alexandra Stanislavsky

Presentation

Healthy subject.

MRI

Block design of a language task in a healthy subject.  Regions of statistically significant activation (p < 0.0001) during a language task are overlayed in false colour over the EPI images.
There is an expected pattern of activation which includes the Broca and Wernike areas, left more than right (note reversed L and R notation) and the anterior cingulate gyrus.

Diagram

fMRI : block design paradigm

A block design fMRI paradigm requires that the subject perform a certain task in time blocks which are interleaved with time blocks of rest.   

For example, in this case the language task was to look at a letter presented on a screen and to generate as many words as possible starting with the letter: the Orthographic Lexical Retrieval (OLR) paradigm.

During rest, the person was asked to refrain from practising the task.

Case Discussion

Functional MRI of language, block design paradigm.

PlayAdd to Share

Case information

rID: 12534
Published: 13th Dec 2010
Last edited: 10th Jul 2018
Tag: fmri
Inclusion in quiz mode: Included

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.