History of anemia with previous history of blood transfusions
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The spleen shows multiple tiny echogenic foci without acoustic shadowing diffusely involving the parenchyma. These are siderotic nodules or Gamna-Gandy nodules.
Gamna Gandy nodules also known as splenic siderotic nodules and fibrosiderotic nodules, are small focal deposits of iron and calcium within fibrous tissue and elastic fibers in spleen resultiing in tiny nodules of less than one millimeter in size.
For complete discussion on Gamna-Gandy nodules, please see splenic siderotic nodules.
- 1. Selçuk D, Demirel K, Kantarci F et-al. Gamna-Gandy bodies: a sign of portal hypertension. Turk J Gastroenterol. 2007;16 (3): 150-2. Pubmed citation
- 2. Chan YL, Yang WT, Sung JJ et-al. Diagnostic accuracy of abdominal ultrasonography compared to magnetic resonance imaging in siderosis of the spleen. J Ultrasound Med. 2001;19 (8): 543-7. Pubmed citation