Gamna-Gandy bodies (nodules)
History of portal vein thrombosis with portal congestion,. Recurrent gastrointestinal bleeding related to portal hypertensive enteropathy.
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A male patient with portal vein thrombosis (with cavernous transformation) and portal hypertensive enteropathy. MR Imaging revealed splenomegaly with multiple small siderotic nodules called Gamna-Gandy bodies (nodules).
Gamna-Gandy bodies are small multiple siderotic lesions in the spleen parenchyma. They contain hemosiderin, calcium, and fibrous tissue. These siderotic nodules are related to portal vein or splenic vein thrombosis, acquired hemochromatosis, hemolytic anemia, leukemia or lymphoma and they represent organized foci of hemorrhage.