Ganglioglioma - optic nerve

Case contributed by A.Prof Frank Gaillard

Suprasellar mass with vivid enhancement involving optic nerve.

Case Discussion



The sections show a moderately hypercellular tumor composed of mature ganglion cells, some of which are binucleated. These are mixed with astrocytic cells showing a mild degree of nuclear pleomorphism. The ganglion cells show strong immunostaining for chromogranin, synaptophysin and neurofilament protein (NFP). No mitotic figures, vascular endothelial cell hyperplasia or necrosis are identified. The features are of ganglioglioma.

DIAGNOSIS: Ganglioglioma (WHO Grade 2).

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Case information

rID: 3887
Published: 21st Jun 2008
Last edited: 17th Oct 2019
Inclusion in quiz mode: Included

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