Gastric gastrointestinal stromal tumor (GIST)

Case contributed by Dr Michael P Hartung


Upper abdominal discomfort.

Patient Data

Age: 70 years

Mostly exophytic, heterogeneously enhancing mass with a few flecks of calcification arising from the gastric fundus/body along the greater curvature. There are a few areas of mucosal/submucosal irregularity which confirms that it arises from or invades the stomach. 

No metastases. 

Case Discussion

Fairly typical appearance of a gastric GIST, characterized by a predominantly exophytic submucosal mass with a few calcifications. Pathologic diagnosis was confirmed at the time of surgery. 


MICROSCOPIC DESCRIPTION: Sections show fragments of tumor composed of spindle cells arranged in fascicles. No mitotic figures seen. Immunohistochemistry positive for CD117 and CD3.

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Case information

rID: 74765
Published: 5th Mar 2020
Last edited: 6th Mar 2020
Inclusion in quiz mode: Included
Institution: Tenwek Hospital

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