Gastrointestinal stromal tumor (GIST)

Case contributed by Abdallah Al Khateeb
Diagnosis certain


Long standing abdominal discomfort. On examination he was found to have a large abdominal mass.

Patient Data

Age: 55-60 years old
Gender: Male

CT abdomen


A large complex, mainly cystic soft tissue mass is arising from the posterior and inferior aspect of the stomach, with thick enhancing internal septations. No calcifications. There is no significant concomitant mesenteric stranding. There are a few small regional mesenteric lymph nodes.

Case Discussion


GROSS DESCRIPTION: The specimen consists of a partial gastrectomy measuring 15 x 101 x 7 cm. Attached to the wall of the stomach is a large cystically dilated mass measuring 21 x 16 x 12 cm. Opening of the mass shows a tumor arising from the wall with a cystic component filled by blood.

SPECIAL STUDIES: The tumor cells are positive for C-kit and CD34, negative for CK, desmin and S-100.

DIAGNOSIS: Epitheloid gastrointestinal stromal tumor.

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