Gastrointestinal stromal tumor-GIST (PET-CT)

Case contributed by Dalia Ibrahim
Diagnosis certain


Incidentally discovered left hypochondrial mass on US.

Patient Data

Age: 60 years
Gender: Female


Nuclear medicine

FDG avid large soft tissue mass lesion is seen projecting from the lateral gastric wall into the gastro-splenic region, with SUV max 16. The mass is fairly defined showing internal areas of breaking down. The mass is abutting the splenic hilum with no separable fat planes in-between. The mass is indenting the gastric wall yet with no significant encroachment upon its lumen. Few small nodules are seen adjacent to the large mass.

Immunohistochemistry report confirmed gastro-intestinal stromal tumor, DOG1 and ckitte positive.

Case Discussion

GISTs are the most common mesenchymal tumors of the gastrointestinal tract.

GISTs are FDG avid tumors on PET-CT. PET-CT is usually used for initial staging or treatment response assessment.

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