Giant cell arteritis
Presentation
Worsening vertigo, ataxia, right leg weakness
Patient Data
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Case Discussion
The patient went on to have bilateral temporal artery biopsies showing: "Multiple small foci of chronic inflammatory cell infiltration around vasa vasora in the adventitia. Some inflammatory cells also appear to target the external elastic lamina. In one section, there is a narrow transmural scar with inflammatory cells, fibroblasts, myxoid collagen, focal fibrinoid material and hemorrhage; giant cells are not seen. The internal elastic lamina in most sections shows short discontinuous foci of fragmentation and focal reduplication with a mild intimal thickening. Although the pattern of inflammation is not entirely classical or fully developed, in this patient demographic features would be strongly suspicious for active temporal arteritis." Unfortunately, despite high dose immune suppression, the patient continued to deteriorate and two months later, with evidence of progressive arterial stenosis on imaging, passed away.