Giant cell granuloma - mandible

Case contributed by Dr Dayu Gai


Right jaw pain.

Patient Data

Age: 15
Gender: Female

Lytic lesion of mandibular ramus centred over the retromolar trigone may be consistent with giant cell granuloma.

Case Discussion

Giant cell granulomas are benign intraosseous lesions, typically occurring in young females. They result from a local inflammatory process, thought to be secondary to trauma. Due to these lesions often being symptomatic, active management is usually performed. Non surgical treatment may include:

  • intralesional corticosteroid injection
  • subcutaneous calcitonin injection

The more "aggressive" giant cell granulomas are treated with either surgical resection or curettage. Nevertheless, recurrence rates are high and quoted to be between 11-49% 1.

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Case information

rID: 43931
Published: 7th Apr 2016
Last edited: 7th Apr 2016
System: Head & Neck
Inclusion in quiz mode: Included

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