Giant cell tumor

Case contributed by Dr Iqbal Naseem


Gradually increasing swelling in wrist from 2 years previously, with 6 months of increasing pain.

Patient Data

Age: 35 years
Gender: Male

Radiograph wrist AP and lateral views showing an expansile lesion giving characteristic "soap bubble appearance" involving the subarticular region of radius with cortical breach on medial aspect.

Also noted is increased overlying soft tissue shadow and osteopenic changes in carpal bones and periarticular areas.

Case Discussion

Giant cell tumors are usually benign, but a few can be malignant, however imaging cannot differentiate between benign and malignant tumors.

GCT usually involves subarticular region distal radius and distal femur, the proximal tibia being the most common site. Occasionally can involve metacarpals, mandible or pelvis.

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