Giant cell tumor of bone

Case contributed by Dr Farzin Soltan Mohammadlou


Chief complaints of left thigh and knee pain since 6 months. Pain increases with walking and activity.

Patient Data

Age: 25
Gender: Female

Zoomed frontal radiograph of knee


A well defined lytic, eccentric medullary epimetaphyseal lesion with diaphyseal extension is seen along the lateral aspect of proximal tibia with cortical thinning and breach. Fairly narrow zone of transition in a mature skeleton. 


CT demonstrates the cortical breach and associated soft tissue component. 

Nuclear medicine

Bone scan identifies increased uptake in the lesion. 

Case Discussion

This patient underwent surgery with open excisional biopsy and her pathology was GCT(Giant xellctumor). Second surgery the whole tumor was removed and tumor bed was filled with cement and proximal tibia fixed with plate.

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