Glandular odontogenic cyst

Case contributed by Dr Brendon Friesen

Patient Data

Age: 50
Gender: Female

43x22  mm  mildly  expanded multiseptated lucent lesion involving left mandible.  


10 month follow-up, post-operative. 

Case Discussion

Radiological differential includes Keratocystic Odontogenic Tumor (Odontogenic Keratocyst) and ameloblastoma.

Histological findings

  • fragments of lamellar bone with surrounding osteoclastic activity
  • occasional multinucleate giant cells seen focally
  • focally, there is a rim of fibrous tissue and is covered by attenuated  squamous  epithelium  with focal areas of ciliated cuboidal type epithelium with areas of mucin vacuoles
  • there is no corrugated parakeratinised squamous  epithelium  seen  which  is typically seen associated with an odontogenic keratocyst

Histological ddx: in view of the presence of ciliated cells, the differentials include periapical cyst, dentigerous cyst with ciliated metaplasia or nasopalatine cyst. 

Final clinical diagnosis

Glandular odontogenic cyst

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Case information

rID: 28660
Published: 7th Apr 2014
Last edited: 7th Oct 2015
System: Head & Neck
Inclusion in quiz mode: Included

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