Glioblastoma

Case contributed by Dr Bruno Di Muzio

Presentation

Seizure.

Patient Data

Age: 60
Gender: Male

CT Brain

Modality: CT

There is a right parietal lobe lobulated and heterogeneous mass which shows necrotic central areas and peripheral enhancement after contrast administration. It causes also local mass effect compressing the right lateral ventricle and with a mild left midline shift. 

MRI Brain

Modality: MRI

The lesion is now better demonstrated as involving the right portion of the splenium of the corpus callosum, posterior portion of the cingulate gyrus and part of precuneus. Ir relatively spared the cortex. Small foci of blooming artefact on the gradient express minor haemorrhagic component. Contrast enhancement is again demonstrated, and the tumour shows also diffusion restriction. 

Case Discussion

The features demonstrated on the MRI helps to put a glioblastoma as the first hypothesis. Glioblastomas have a preferential spreading along the condensed white matter tracts such as corticospinal tracts and corpus callosum.

The case was histologically confirmed as glioblastoma (WHO grade IV). 

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Case Information

rID: 39641
Case created: 13th Sep 2015
Last edited: 11th Oct 2015
Tag: rmh
Inclusion in quiz mode: Included

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