Glioblastoma

Case contributed by Dr Ali Abougazia

Presentation

Confusion.

Patient Data

Age: 5
Gender: Male
Modality: MRI

Left high frontal irregular space occupying lesion is seen eliciting low T1 and high T2/FLAIR signal with areas of high T1 and low T2/FLAIR signals (indicating met-Hb) and peripheral irregular contrast enhancement. The lesion exerts mass effect and is seen surrounded by vasogenic edema. MR spectroscopy shows marked elevation of the choline with depression of the normal markers (N-acetyle aspartate and creatine) as well as small lipid / lactate doublet, with similar changes seen in the edema around the lesion.

Complete agenesis of the corpus callosum.

Case Discussion

Pathologically proven high grade glioma; glioblastoma (WHO grade IV), and complete agenesis of the corpus callosum.

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Case Information

rID: 22923
Case created: 4th May 2013
Last edited: 28th Nov 2015
Inclusion in quiz mode: Included

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