Glioblastoma

Case contributed by A.Prof Frank Gaillard
Modality: MRI

Pending. 

Case Discussion

Final Diagnosis:

Brain, left frontal: Astrocytoma grade 4/4 (glioblastoma) using the Daumas-Duport grading system.

Microscopic Description:

Sections show the specimen to consist predominantly of necrotic tissue, in areas containing viable glioma that is high grade. The tumor cells display small cell morphologic characteristics, possible oligodendroglial features, and astrocytic elements with a fibrillar appearance. Mitotic figures are identified. Vascular proliferation is observed, including glomeruloid aggregates proliferating capillaries. As previously mentioned, tumor necrosis is extensive. Abnormally large ectatic vascular structures are also seen, and are consistent with a vascular malformation. Several vessels are thrombosed.

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Case Information

rID: 5292
Case created: 31st Dec 2008
Last edited: 28th Nov 2015
Inclusion in quiz mode: Included

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