Glioblastoma

Case contributed by A.Prof Frank Gaillard

Presentation

Adult patient with increasing headache.

MRI Brain (selected images)

Modality: MRI

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Case Discussion

MRI demonstrates a large mass in the superior part of the right temporal lobe. It exerts significant mass effect and is surrounded by vasogenic oedema. The mass itself is heterogeneously low on T1, and demonstrates a very high T2 signal region centrally, suggestive of a necrotic centre. 

Following administration of contrast the margins enhance irregularly. 

Features are most consistent with a high-grade (WHO grade IV) primary glial tumour. The differential would include a solitary metastasis, or less likely a cerebral abscess (no restricted diffusion however makes this unlikely). 

Following biopsy this was confirmed to ab a glioblastoma.

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Case Information

rID: 8939
Case created: 10th Mar 2010
Last edited: 2nd Dec 2015
Tags: gbm, glioma
Inclusion in quiz mode: Included

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