Glioblastoma

Case contributed by Dr Ahmed Abd Rabou

Presentation

Left hemiparesis and headache

Patient Data

Age: 78-year-old
Gender: Male

MRI Brain

Modality: MRI

Right parietooccipital irregular intra-axial heterogeneous lesion surrounded by perifocal oedema and exerting a positive mass effect on the ipsilateral lateral ventricle. It displays heterogeneous enhancement with a haemorrhagic component at the posterior aspect of this lesion.

MRI Brain (Spectroscopy)

Modality: MRI

Magnetic resonance spectroscopy reveals:

  • reduced NAA reflecting neuronal damage
  • elevated choline denoting rapid membrane turnover
  • marked lipid and lactate rise indicating intra lesional necrosis

Case Discussion

The case was confirmed histologically.

Glioblastoma is a highly malignant primary brain tumor (WHO IV) and represents the most common primary malignant brain tumour.

PlayAdd to Share

Case Information

rID: 22766
Case created: 21st Apr 2013
Last edited: 2nd Nov 2016
Inclusion in quiz mode: Included

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.