Glioblastoma

Case contributed by Dr Dalia Ibrahim

Presentation

Dizziness.

Patient Data

Age: 45 years
Gender: Female
MRI

Left posteromedial temporal lesion, involving the most posterior parts of the parahippocampal and cingulate gyrus and extending into the splenium of the corpus callosum. It shows heterogeneous signal with large necrotic center and marginal contrast enhancement. The lesion is surrounded by extensive vasogenic edema signal involving the splenium of the corpus callosum.

Based on radiological findings, high grade glioma was considered.

Photo

Pathology after excision revealed glioblastoma, grade IV

Case Discussion

Glioblastomas are typically large tumors at diagnosis. They often have thick, irregular-enhancing margins and a central necrotic core, which may also have a hemorrhagic component. They are surrounded by vasogenic-type edema, which in fact usually contains infiltration by neoplastic cells.

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Case information

rID: 87499
Published: 5th Mar 2021
Last edited: 25th Mar 2021
Inclusion in quiz mode: Included