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Large heterogeneously enhancing mass with regions of peripheral nodularity. The adjacent cortex is thickened. Marked elevation of choline.
The patient went on to have a resection which confirmed the diagnosis of glioblastoma.
- Neoplastic cells positive for GFAP (polyclonal)
- Negative for EMA
- Strong nuclear staining for P53 (D0-7)
- Ki-67 positive in 15%