Presentation
Headaches.
Patient Data
Ring-enhancing mass in the right temporo-parietal region. Some nodular componenets. Surrounding edema. Blooming on GRE indicative of intralesional hemorrhage.
Case Discussion
The patient went on to have surgery.
Histology
The biopsy shows a moderately cellular astrocytic tumor. The astrocytes have enlarged elongated and hyperchromatic nuclei. These are admixed with scattered foamy macrophages. Mitoses are identified. There are foci of endothelial cell hyperplasia. Necrosis is also seen, along with necrotic blood vessels. The features are those of glioblastoma multiforme.
FINAL DIAGNOSIS: glioblastoma
Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a glioblastoma NOS.
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