Glioblastoma NOS

Case contributed by Assoc Prof Frank Gaillard



Patient Data

Age: 55 years
Gender: Male

Ring-enhancing mass in the right temporo-parietal region. Some nodular componenets. Surrounding edema. Blooming on GRE indicative of intralesional hemorrhage. 

Case Discussion

The patient went on to have surgery. 


The biopsy shows a moderately cellular astrocytic tumor.  The astrocytes have enlarged elongated and hyperchromatic nuclei.  These are admixed with scattered foamy macrophages.  Mitoses are identified. There are foci of endothelial cell hyperplasia.  Necrosis is also seen, along with necrotic blood vessels.  The features are those of glioblastoma multiforme.

FINAL DIAGNOSIS: glioblastoma


Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a glioblastoma NOS

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Case information

rID: 10223
Published: 24th Jul 2010
Last edited: 13th Aug 2019
Tag: glioma
Inclusion in quiz mode: Included

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