Presentation
Left hemiparesis and headache
Patient Data
Age: 80 years
Gender: Male
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Right parietooccipital irregular intra-axial heterogeneous lesion surrounded by perifocal edema and exerting a positive mass effect on the ipsilateral lateral ventricle. It displays heterogeneous enhancement with a hemorrhagic component at the posterior aspect of this lesion.
Magnetic resonance spectroscopy reveals:
- reduced NAA reflecting neuronal damage
- elevated choline denoting rapid membrane turnover
- marked lipid and lactate rise indicating intralesional necrosis
Case Discussion
The case was confirmed histologically.
Glioblastoma is a highly malignant primary brain tumor (WHO IV) and represents the most common primary malignant brain tumor.
Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a glioblastoma NOS.
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