Glioblastoma NOS

Case contributed by Frank Gaillard , 31 Dec 2008
Diagnosis certain
Changed by Henry Knipe, 28 Nov 2015

Updates to Study Attributes

Updates to Study Attributes

Findings was added:

Pending. 

Images Changes:

Image 2 MRI (T1 C+) ( update )

Position was set to .

Image 4 MRI (T2) ( update )

Position was set to .

Updates to Case Attributes

Title was changed:
Glioblastoma multiforme - very vascular
Body was changed:

Final Diagnosis:

Brain, left frontal: Astrocytoma grade 4/4 (glioblastoma multiforme) using the Daumas-Duport grading system.

Microscopic Description:

Sectionsshow the specimen to consist predominantly of necrotic tissue, in areascontaining viable glioma that is high grade. The tumor cells displaysmall cell morphologic characteristics, possible oligodendroglialfeatures, and astrocytic elements with a fibrillar appearance. Mitoticfigures are identified. Vascular proliferation is observed, includingglomeruloid aggregates proliferating capillaries. As previouslymentioned, tumor necrosis is extensive. Abnormally large ectaticvascular structures are also seen, and are consistent with a vascularmalformation. Several vessels are thrombosed.

  • -<p>Final Diagnosis:</p><p>Brain, left frontal: Astrocytoma grade 4/4 (<a href="/articles/glioblastoma-multiforme">glioblastoma multiforme</a>) using the Daumas-Duport grading system.</p><p>Microscopic Description:</p><p>Sections
  • -show the specimen to consist predominantly of necrotic tissue, in areas
  • -containing viable glioma that is high grade. The tumor cells display
  • -small cell morphologic characteristics, possible oligodendroglial
  • -features, and astrocytic elements with a fibrillar appearance. Mitotic
  • -figures are identified. Vascular proliferation is observed, including
  • -glomeruloid aggregates proliferating capillaries. As previously
  • -mentioned, tumor necrosis is extensive. Abnormally large ectatic
  • -vascular structures are also seen, and are consistent with a vascular
  • -malformation. Several vessels are thrombosed.</p>
  • +<p>Final Diagnosis:</p><p>Brain, left frontal: Astrocytoma grade 4/4 (<a href="/articles/glioblastoma">glioblastoma</a>) using the Daumas-Duport grading system.</p><p>Microscopic Description:</p><p>Sections show the specimen to consist predominantly of necrotic tissue, in areas containing viable glioma that is high grade. The tumor cells display small cell morphologic characteristics, possible oligodendroglial features, and astrocytic elements with a fibrillar appearance. Mitotic figures are identified. Vascular proliferation is observed, including glomeruloid aggregates proliferating capillaries. As previously mentioned, tumor necrosis is extensive. Abnormally large ectatic vascular structures are also seen, and are consistent with a vascular malformation. Several vessels are thrombosed.</p>
Diagnostic Certainty was set to .

Tags changed:

  • findings

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