Glioblastoma NOS

Case contributed by Dr Ahmed Abd Rabou

Presentation

Headache and disturbed conscious level.

Patient Data

Age: 60 years
Gender: Male
MRI

MRI Brain

Large left temproparietal paramedian intra-axial space occupying lesion that is resting medially on the falx cerebri and involves the left forceps major fibers as well as the splenium of the corpus callosum. The lesion displays low T1, bright T2/FLAIR signal with extensive central necrosis and peripheral marginal and nodular enhancement. There are central areas of mild diffusion restriction and susceptibility artifacts. It is surrounded by moderate perifocal edema and exerts positive mass effect in form of anterior displacement of the occipital horn of ipsilateral lateral ventricle and 1 cm rightward midline shift.

Case Discussion

The imaging findings are characteristic of a glioblastoma

The patient underwent surgery and the diagnosis was confirmed histologically.

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumours, this tumour would, therefore, be designated as a glioblastoma NOS

 

PlayAdd to Share

Case information

rID: 39024
Case created: 16th Aug 2015
Last edited: 25th May 2017
Inclusion in quiz mode: Included

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.