Glioblastoma NOS

Case contributed by Dr Ahmed Abdrabou


Headache and disturbed conscious level.

Patient Data

Age: 60 years
Gender: Male

MRI Brain

Large left temproparietal paramedian intra-axial space occupying lesion that is resting medially on the falx cerebri and involves the left forceps major fibers as well as the splenium of the corpus callosum. The lesion displays low T1, bright T2/FLAIR signal with extensive central necrosis and peripheral marginal and nodular enhancement. There are central areas of mild diffusion restriction and susceptibility artifacts. It is surrounded by moderate perifocal edema and exerts positive mass effect in form of anterior displacement of the occipital horn of ipsilateral lateral ventricle and 1 cm rightward midline shift.

Case Discussion

The imaging findings are characteristic of a glioblastoma

The patient underwent surgery and the diagnosis was confirmed histologically.

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a glioblastoma NOS


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Case information

rID: 39024
Published: 19th Aug 2015
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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