Presentation
Intractable headache and history of craniotomy two months ago.
Patient Data
Age: 65 years
Gender: Female
From the case:
Glioblastoma NOS
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Right parietal craniotomy
Irregular heterogenous partially-enhancing intra-axial mass, with a cystic/necrotic component ( 35*41*46 mm ), prominent vasogenic edema and involvement of occipital horn of lateral ventricle.
High signal foci in T2 and FLAIR sequences in the subcortical and periventricular the white matter of both cerebral hemispheres depicts microvascular ischemic events.
Case Discussion
Microscopic:
The brain glial tumor is extensively necrotic with palisading of tumor cells, areas of hemorrhage and microvascular proliferation. The tumor is moderately cellular, composed of atypical cells and many gemistocytes.
Diagnosis:
Glioblastoma, NOS, WHO grade IV.
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