Glioblastoma NOS

Case contributed by Dr Muhammad Saad Ahmed
Diagnosis possible

Presentation

Headache and seizures on and off for 4 months.

Patient Data

Age: 50 years
Gender: Female
ct
  • a well-circumscribed hypodense lesion with thickened margins and areas of central necrosis in the right frontal lobe, showing mild enhancement on post-contrast images.
  • associated with moderate vasogenic edema and compressive effects over the frontal horn of the right lateral ventricle with minimal contralateral midline shift. 
  • another lesion noted at the right frontal region, at the high vertex posteriorly, represents a satellite lesion.

Case Discussion

Glioblastomas NOS are large tumors at the time of diagnosis. They frequently have thick, irregular-enhancing margins and a central necrotic core. 

The patient was lost to follow up so histopathological diagnosis is not available. However, the patient has no known malignancy so glioblastoma NOS is the more favorable diagnosis.

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